Chaos reaped by Storm Christoph has now caused flooding around a factory producing the crucial Covid vaccine.
Teams have been working through the night to protect the factory in Wrexham, North Wales, that is making the Oxford/AstraZeneca jab.
And a flurry of new ice warnings have been issued for much of the Midlands, North of England, Wales, Scotland and Northern Ireland, compounding the situation.
Hundreds of people were told to leave their homes overnight as Storm Christoph caused widespread flooding across the UK.
Some 2,000 properties in the East Didsbury, West Didsbury and Northenden areas of Greater Manchester were due to be evacuated on Wednesday night because of rising water levels, the city council said.
People were also asked to leave their homes in parts of Ruthin and Bangor on Dee in North Wales, and Maghull in Merseyside.
It comes as heavy rain and snow continued to fall across England and Wales, with many rivers at “dangerously high levels”, the Environment Agency said.
Four “severe” flood warnings, meaning there is a danger to life, were issued by the agency for the River Mersey at Didsbury and Northenden, and in Maghull.
A fifth was issued by Natural Resources Wales for Bangor on Dee.
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